Cent Cinquante Neuf

All-day pregnancy sickness has kicked me in the ass this week. I’m basically doing the bare minimum in terms of daily tasks (feed self, feed dogs, bathroom tasks), and then trying to sleep away the nausea in between. When I am awake, I feel like I’ve got the worst hangover of my life- nausea, headache, flu-like symptoms. My food aversions are terrible too- all foods are grossing me out. I had a bottle of Diclectin (Diclegis) leftover from last pregnancy, and finally decided that it was time to take it. I started it last night, and so far, it hasn’t kicked in yet (heard it can take several days to work) and makes me feel super groggy. I’ve never responded well to Unisom or Benedryl as a sleep aid- it keeps me drowsy but unable to sleep, contrary to what many other people experience (Diclectin as a wonderful sleep aid). 

This morning I dry heaved several times because I didn’t get my oatmeal in my tummy fast enough. However, I was able to finish an entire lunch and had a snack this afternoon. That’s progress!

So today was my viability ultrasound. 

And I have good news….

We have a heartbeat!

Dumplin’ is measuring 6 weeks 6 days (a little short of the 7 weeks 3 days that is based on my IVF dates), and has a heartbeat of 159!

There was also another empty sac measuring 0.6cmx0.4cmx0.3cm that could either be a subchorionic hemorrhage or a second gestational sac. Judging by the shape of it (sphere-like vs. crescent-like), RIP Dumplin’s Vanishing Twin.

So I’m not sure if we’ve graduated from the fertility clinic, but given the congratulations!, random loot bag they gave me, plus the requisition for my OB or midwife to sign off on (for me to do a 12 week screening ultrasound there), I’m guessing we did!



Loot bag (with a post-it note that says ” For OB patients only”)

What was inside the loot bag.

So yeah! They want me to start tapering off my prednisone in two weeks, but after consulting with some other RPL friends as well as investigating other protocols for NK cytokine activity, I’ve decided to go rogue and start tapering at 15 weeks instead. 

The progesterones and Fragmin they want me to stop abruptly at 12 weeks.

The aspirin I continue until 32 weeks. 

The synthroid I will continue as per my endocrinologist’s recommendations.

This week I will have my last intralipid infusion as well.

We are very happy to have viability. Given our losses, it’s difficult to be as bright-eyed and bushy tailed about it, as we know anything can happen. But we are taking it day by day, and are grateful that this little soul chose us.

And of course, we celebrated with some awesome authentic Chinese food for lunch! 



Tomorrow, we meet with our midwives for the first time! 

Thank you everyone for keeping us in your thoughts. Please continue to, as the next five weeks will be difficult as well. 


FET#4: Protocol

There are a lot of meds involved in our FET this round, and I thought that I’d like to document it, both for myself, but also to help anyone else who is also going through this. The days refer to cycle day, and non-medical supplementation is in brackets (Chinese Medicine herbs).

Days 3-16: Estrace 6mg daily

Days 3+: ASA 81mg daily

Day 13: Intralipids

Day 17+:
7:30am: Prednisone 10mg, Estrace 2mg, Pink PregVit, 100mg Endometrin, (1000IU Vitamin D, Yuan Support Formula- 4 tablets)
3:30pm: Endometrin 100mg, (Yuan Support Formula)
Dinner time: ASA 81mg, Blue PregVit Folic 5
11:30pm: 5000IU Fragmin, 2mg Estrace, 300mg Prometrium, 100mg Endometrin, levothyroxine 25mcg, (omega 3 fish oils, Yuan Support Formula)

Day 21: Frozen Embryo Transfer

Day 31: HCG beta test

Day 33: Repeat HCG beta test

Sometime after Day 33: Intralipids

Tips:

– Set time alarms on your phone so that you take your meds at the proper times.

– But a pill schedule case like this to organize yourself:

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– inject the Fragmin super slowly

– protect your underpants from leaky Endometrin using long and wide, but super thin panty liners. Better yet- make your own cloth ones, they are so much more comfortable

– clean your lady parts after Endometrin messes, or else it seems to burn down there

I just started the huge combo of meds today, and let me tell you, the Fragmin burns like a B$&@H! I was perfectly fine with the Lupron, Follistim, and Ovidrel injects during my stimulation phase, but this needle would not break the skin without significant force, and while I plunged very very slowly, the medication itself causes a strong burning sensation. I had DW hold my fat roll for me because I needed two hands to steadily depress the plunger, and it felt like she was pinching me as tightly as she could with fingernails (she wasn’t- that’s just what the Fragmin felt like going in). Anyway, I will find a way to make it work, as it needs to be done daily, but right now it is a not-so-distant unpleasant memory. Some advice: have someone else inject it for you, inject the drug very slowly, stop and catch your breath after the burning feeling, inject some more, and so on.

We also keep a stash of homemade organic tea tree and witch hazel wet naps by the toilet to help me “wipe up” any nasty Endometrin leakage (vaginal suppository). I am back to wearing large Cadillac-sized panty liners again too (so as to not ruin my underwear), so the wipes help to prevent some of the chaffing I experienced last pregnancy.

Immune Testing Results

You may recall that I had some testing done after it was revealed that I miscarried a chromosomally normal embryo back in September.

Here’s the post about it, if you don’t remember.

Anyway, it’s been three weeks now, and the results have come in for most of them, except for the natural killer Th1/Th2, the $640 test that is sent to California for testing.

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It has all come back normal.

I’m skeptical on many fronts, as I have very little confidence in the reliability of lab work that isn’t repeated. In 2010, I had some abnormal blood work results that forced me, my GP, and some specialists down an ovarian cancer rabbit hole. The abnormal blood work was corroborated by some abnormal ultrasound findings, which suggested a rather large multi-chambered tumour on my right ovary. The blood work was repeated a month after I had given away my chiropractic practice thinking that I was going to die (who wants to work during their last year of life?), and was totally normal. A slew of medical specialists were convinced to see what they wanted to see, all because of what we speculated to likely be a “mix up” in the blood lab.

Anyway, I am not sure what to make of all of this. I’m not sure that my RE’s testing is comprehensive, but we are led to believe that my immune system did not kill the embryo.

If our embryo is truly chromosomally normal (I question this sometimes too- though I’m told that it’s a bit more reliable because they culture the samples for a long time to distinguish between mama and embryo tissue), and my immune system did not kill our embryo, then what did?

As mentioned above, I’m still waiting on the NK cells results. How much do you wanna bet that they will be normal too?

Right now we’re waiting for my period to begin (in probably a week or so), and then we’re off to embryo transfer #4, with our last embryo. I’m particularly anxious about the chance of success with this transfer, as we’re only transferring one. Each of our previous transfers, we’ve transferred two. I’m trying to remain hopeful, as this embryo deserves to come home, and be loved. It’s just difficult to be hopeful when 2013 and 2014 have been filled with disappointment. I’m trying to find meaning in it, maybe something that I’m supposed to learn, but I’m struggling and it’s really breaking my spirit.

Anyway, lone star, you are so loved. Come home and stay with us forever. Your mama et maman have been hoping and praying for you to choose us.